Senator Dr. Trevor T. J. DeVaney
PhD., BSc. Joint Hons., HNC., ONC., MCP.
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Senator der Med. Uni. Graz |
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Safety and security officer |
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Medonline Partner |
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IT Partner |
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Radiation Protection Officer |
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Lecturer |
Personal details
I was born in London in 1959 in the London University Hospital in Gower Street London Great Britain. After enjoying a
comprehensive education at Simon Langton Grammar School in Canterbury I continued my efforts at further
education on a Day-Release basis as technician at the University of London's agricultural college Botany
Department in Wye Kent where I was responsible for the teaching
laboratories and some research.
I then pursued my academic career further
in that I read at University College Cardiff, Microbiology and Genetics for
which I obtained my joint degree with honours. I also have a Higher National
Certificate in Applied Biology specializing in microbiology as well as an
O.N.C. in Chemistry Specialising in industrial chemistry that I obtained during
my time in Wye. I have resided since 1984 in Austria. I married Silvia on the
21 October 2000 and gained three wonderful children
Monica, Valentina and Stefanie.
I qualified for my PhD at University College
Cardiff in 2004 and have published several articles on the investigation of
cancer invasiveness in vitro.
Scientific publications,
presentations and CV in German
Curriculum, Presentations and
Publications in English
In 2007 I Patented an invention enabling phase
contrast microscopy of living cells in 6 to 96 well plates which eliminates the
effects of the meniscus induced loss of phase contrast.
A
more explicit explanation can be found here from a poster presented at the Linz
Congress
Recent Publications:-
** Habermann,
W; Schmid, C; Neumann, K; Devaney,
T; Hammer, HF
Reflux
Symptom Index and Reflux Finding Score in Otolaryngologic
Practice.
J Voice. 2011; 108(8b):
Human
Intraoral Harvested Mesenchymal Stem Cells:
Characterization, Multilineage Differentiation
Analysis, and 3-Dimensional Migration of Natural Bone Mineral and Tricalcium Phosphate Scaffolds.
J Oral Maxillofac
Surg. 2011
Lysophosphatidic
acid receptor activation affects the C13NJ microglia cell line proteome leading
to alterations in glycolysis, motility, and cytoskeletal architecture.
Proteomics.
2010; 10(1): 141-158
Cloning
and characterisation of GIRK1 variants resulting from alternative RNA editing
of the KCNJ3 gene transcript in a human breast cancer cell line.
J Cell Biochem. 2010; 110(3): 598-608.
Rezania,S; Chouyang,L; Gorischek,A; Devaney,T; Regitnig,P; Bauernhofer,T; Schreibmayer,W;
Influence
of G-protein activated inwardly rectifying potassium channel on vital
parameters of breast cancer cells
Doctoral Day; 4.11.2011; 2011. [Poster]
A
new biophysical method to measure cancer cell motility and invasiveness to
evaluate new anticancer compounds.
; Okt, 2009; Dykabiri,
Turkey. 2009. [Keynote
lecture]
Wagner, V; Gorischek, A; Stadelmeyer, E; DeVaney, T; Schreibmayer, W;
Bauernhofer, T
Expression
and characterization of G-protein activated potassium channel splice variants.
joint
ZMF & Doctorial Day ; NOV 4-5, 2009; Graz, AUSTRIA. 2009. [Poster]
Growth
of squamous carcinoma cells under the influence of
chemotherapeutic agents
Altex2008; 25(1):-15th Congress on Alternatives
to Animal Testing – Linz 2008& 12th Annual Meeting of MEGAT – Middle
European Society for Alternative Methods to Animal Testing ; 19.21 Sept 2008;
Linz. [Poster]
DeVaney, TTJ; Sax, W; Platzer, F
Correction of optical refraction artefacts in multiwell plates for live cell imaging.
Focus on Microscopy 2008
http://www.focusonmicroscopy.org/2008/PDF/164_DeVaney.pdf 2008; 152.-Focus on
Microscopy 2008. ; April 13-16, 2008; Osaka, Japan. [Oral
Communication]
Research in progress
Metastasierung
und Zellmotilität
Die Zellmotilität
ist ein entscheidender Faktor im Prozess der Metastasierung. In diesem Bereich
erforschen wir die involvierten zellulären Prozesse und die resultierenden
Effekte aus der Anwendung von Chemotherapeutika.
Spheroid confrontation invasion assays
3D Spheroid
Konfrontations-Untersuchungen ermöglichen die Ermittlung des Grades des
metastatischen Potentials von verschiedenen Zelllinien ohne den Einsatz von
Tierversuchen. Unter Anwendung von digitaler Bildbearbeitung können die aus
diesen Untersuchungen gewonnenen Daten zur Überwachung und Evaluierung von
Tumoren und deren Behandlung dienen.
Analyse von
Wachstum auf synthetischem Knochenersatz
Unter Verwendung von 3D Rekonstruktion und timelapse Mikroskopie kann die Kolonisation von
synthetischen Knochenersätzen durch Osteoblasten
direkt beobachtet werden.
Analyse von Konfokalbildern
Konfokale Bildgebung und Dekonvolution bei der Weiterverarbeitung ermöglichen
hochauflösende Bildgebung der zu untersuchenden
Gewebe. Der Einsatz von Laserabtatstung ermöglicht
die Rekonstruktion von dreidimensionalen Bildern, welche ein höheres Maß an
Information über zelluläre Prozesse liefern, die eine maßgebliche Rolle bei
Bewegung und invasiven Vorgängen in Gewebe und Strukturen spielen.
Quantitative
Analyse von 3D-Invasion
Mittels Computeranalysen von subjektiven
Entscheidungen von Experten können die qualitativen Entscheidungen
quantifiziert werden und entsprechende Analysealgorithmen entwickelt werden.
Cell motility
and chemotoxic agents
Cell movements in and through tissues